Study identifies TBK1 as key to overcoming CAR T resistance

Russell W. Jenkins, MD, Ph.D., a physician investigator in the Krantz Family Center for Cancer Research at the Mass General Cancer Center and an assistant professor of Medicine at Harvard Medical School, is senior author of a new study in Cancer Immunology Research, “TBK1 is Identified as a Therapeutic Strategy to Enhance CAR T-Cell Efficacy Using Patient-Derived Organotypic Tumor Spheroids”.
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Researchers find new biomarkers for osteoporosis diagnosis and treatment

Researchers at Hospital for Special Surgery (HSS) have pinpointed a cellular target that could enhance the way osteoporosis and other metabolic bone diseases are diagnosed and treated. The findings, published recently in JCI Insight, reveal that circulating osteoclast precursor cells (cOCPs) play a pivotal role in bone loss. The study is also the first of its kind to establish a connection between cellular biomarkers and osteoporosis, offering a potential pathway for earlier detection and more effective therapies.
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Transplant of frozen testicular tissue after chemotherapy during childhood provides hope for fertility restoration

In boys who, before starting puberty, undergo radical treatments that can affect their fertility, testicular tissue can be preventively removed and frozen. This is done to preserve testicular stem cells, the precursors of sperm cells. Chemotherapy and radiation therapy can destroy these cells, leading to infertility later in life.
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Oncology Based in-Vivo CRO Business Research Report 2024-2030: Expansion in Rare Cancers, Pediatric Oncology, and Early-Phase Trials Expands Market Opportunities – ResearchAndMarkets.com

DUBLIN–(BUSINESS WIRE)–The “Oncology Based in-Vivo CRO – Global Strategic Business Report” report has been added to ResearchAndMarkets.com’s offering. The global market for Oncology Based In-Vivo CRO was estimated at US$1.5 Billion in 2023 and is projected to reach US$2.5 Billion by 2030, growing at a CAGR of 7.0% from 2023 to 2030. This comprehensive report provides an in-depth analysis of market trends, drivers, and forecasts, helping you make informed business decisions. Oncology-based In-
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