An energy trap for tumor cells: Researchers find enzyme blockade halts liver cancer growth
Glycolysis is a central metabolic pathway by which cells obtain energy from sugar. Cancer cells in particular have long been thought to depend on the energy obtained through glycolysis, a phenomenon known as the Warburg effect. Today we know that cancer cells can use energy sources more flexibly than previously thought. Even when glycolysis is blocked, they survive by obtaining their energy through the respiratory chain.
Heart cell survival in space sheds light on better treatment strategies on Earth
A team of researchers led by Emory’s Chunhui Xu recently found that heart muscle cells can grow and survive in the microgravity environment of space. The team’s findings, published in Biomaterials, show promise for developing hardier heart cells that could effectively repair damaged hearts in cell therapy—the process of transplanting millions of heart cells to repair damaged hearts—on Earth.
UK researchers call for renewed efforts in cancer vaccine development
UK oncology researchers have come together to write the first-ever national thought leadership strategy report into cancer vaccine advances and the opportunities these present for those affected by cancer. The strategy report has been published in the journal Cambridge Prisms: Precision Medicine.
Developing 3D-printed surgical guides for cardiovascular surgeries
A research team led by Ida Anna Cappello of the Heart Rhythm Management Centre of the University Hospital Brussels (VUB) has made significant strides in the field of biomedical engineering by developing innovative 3D printed surgical guides for cardiovascular procedures. The team’s research, conducted in close collaboration with cardiologists and cardiac surgeons, holds the potential to revolutionize surgical accuracy in complex heart surgeries.
Research assesses how infertility treatments can affect family and work relationships
Infertility is a problem that affects between 8% and 12% of couples of reproductive age worldwide. For some of them, the problem interrupts a life project, which is the desire to have children and build a family. Advances in technology and medicine have made assisted reproductive treatments possible, but they can be physically and psychologically draining for the couples involved, especially because of expectations of results that may not be achieved.
COPD is the sixth leading cause of death in the US
Chronic lower respiratory diseases, including chronic obstructive pulmonary disease (COPD), are the sixth leading cause of death in the United States, according to the U.S. Centers for Disease Control and Prevention (CDC). The CDC’s National Center for Health Statistics released its “Deaths: Leading Causes for 2022” final report, ranking the 10 leading causes of death.
Study investigates trends in alcohol and other drugs in injury-linked and fatal road crashes over a decade
Methylamphetamine is the most common illicit drug found in injured and fatal car drivers and motorcyclists in Victoria from 2010 to 2019, Monash University-led research has found.
Exercise improves brain function, possibly reducing dementia risk
A study led by scientists at Rutgers University-New Brunswick has shown that specialized cells involved in how the body responds to insulin are activated in the brain after exercise, suggesting that physical activity may directly improve brain function.
Intensive blood pressure control linked to reduced cognitive decline risk
A new study by researchers at Wake Forest University School of Medicine shows that only 3.5 years of intensive blood pressure control continues to significantly reduce the risk of mild cognitive impairment or dementia long after stopping this treatment in adults with hypertension and high cardiovascular risk.
Clinical practice guidelines updated for management of stroke rehab
In clinical practice guidelines jointly issued by the U.S. Department of Veterans Affairs and U.S. Department of Defense and published online Jan. 21 in the Annals of Internal Medicine, updated recommendations are presented for the management of stroke rehabilitation.