Oncology & Cancer

Breast cancer often relapses in distant organs even when complete regression of primary tumors is achieved after initial treatment. Dormant and persistent disseminated tumor cells (DTCs) have been observed in animals with non-metastatic disease, which cannot be targeted by systemic chemotherapy.

Patients in a structured exercise program experienced a 37% lower risk of death and a 28% reduction in recurrence or development of new cancers compared to those who received only health education materials, a recent study found.

Cedars-Sinai investigators have discovered that large oncosomes—fluid-filled sacs released into the bloodstream by aggressive cancer cells—contain a consistent set of molecules across cancer types. Their findings, published in Cell Reports Medicine, highlight large oncosomes in the blood as a possible method of diagnosing and monitoring malignancies.

Researchers are one step closer to developing a simple, at-home test to prevent cervical cancer or treat it early, shows a study from University of Florida Health Cancer Center and Purdue University researchers.

For decades, oral health care has mainly focused on preventing cavities and gum disease. However, scientific research has increasingly highlighted the importance of the oral microbiome—a set of microorganisms that naturally inhabit the oral cavity. Recent studies have shown links between imbalances in this microbial ecosystem and the development of head and neck cancers, as well as a growing body of evidence associating it with colorectal cancer.

Research led by Samsung Medical Center finds breast cancer survivors exhibit an 8% lower risk of Alzheimer’s dementia (AD) compared with cancer-free individuals, with radiation therapy potentially contributing to the reduced risk.

A multinational team of researchers, co-led by the Garvan Institute of Medical Research, has developed and tested a new AI tool to better characterize the diversity of individual cells within tumors, opening doors for more targeted therapies for patients.

Bowel cancer is no longer just a disease of the elderly. In Australia and around the world, there’s been a concerning rise in bowel cancer cases among people under 50, and no one yet knows exactly why.

A new cancer treatment that delivers radiation directly to tumors by targeting two key markers simultaneously has been shown to be safe and effective in human trials. Acting like a “smart missile,” the dual-targeting radiopharmaceutical is designed to attach to two vulnerable sites on cancer cells, enabling more precise and potent therapy. Early results show that nearly 90% of patients experienced either tumor shrinkage or disease stabilization. These findings were presented at the Society of Nuclear Medicine and Molecular Imaging 2025 Annual Meeting.

The International Osteoporosis Foundation (IOF) Bone and Cancer Working Group has released a comprehensive review detailing the often under-recognized impact of modern anti-cancer treatments on bone health.