A pathological partnership between Salmonella and yeast in the gut

University of Illinois Chicago-led researchers have found that a common gut yeast, Candida albicans, can help Salmonella Typhimurium take hold in the intestine and spread through the body. When interacting, a Salmonella protein called SopB prompts the yeast to release arginine, which turns on Salmonella’s invasion machinery and quiets the body’s inflammation signals.