MyBlueDots

Wireless device enables precise activation of light-sensitive pain drugs in animal study

Photoactivable drugs are activated when irradiated by a beam of light—via an optical fiber—thus generating a controlled and local therapeutic effect on target tissues. Now, a scientific team has pioneered a new breakthrough in the field of photopharmacology with the design of the first wireless device capable of remotely activating a photoactivable drug and causing it to have therapeutic effects on specific organs.
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Brain’s ‘waste disposal network’ is shaped by neural activity, study finds

Over the past decade, intensive studies have shown that the brain’s meningeal lymphatic system acts as the brain’s “waste disposal network,” maintaining homeostasis by clearing metabolic waste and transporting immune cells. However, the mechanism underlying its developmental regulation remains unknown. How does this intricate system form, and which cells or signals govern its specific spatial arrangement in the meninges?
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Q&A: Silent scorpion-sting epidemic in Brazil driven by urbanization and climate change

Prof Eliane Candiani Arantes heads the Laboratory of Animal Toxins at the School of Pharmaceutical Sciences of Ribeirao Preto, University of São Paulo (USP) where her group is working with toxins found in the venom of the Crotalus durissus terrificus rattlesnake and the Tityus serrulatus scorpion. They also study the venoms of scorpions from the Amazon region, which are still not well understood.
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