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Three caregiver personas emerge from dementia medication management study

Understanding the strategies and unmet needs of caregivers managing medications for people with Alzheimer’s disease or related dementias may improve the lives of both caregivers and patients. A recent study, whose authors include Regenstrief Institute Research Scientists Noll Campbell, PharmD, M.S., and Malaz Boustani, M.D., MPH, describes the strategies and unmet needs of caregivers managing medications for people with Alzheimer’s disease or related dementias.
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Female-specific mechanism for energy expenditure discovered in brown adipose tissue

Higher activity of PGC-1α enables brown fat cells in females to achieve thermogenic activity and energy expenditure compared to males, reveals a study conducted in Japan. This research demonstrates that PGC-1α protein promotes phospholipid synthesis, which strengthens mitochondria of brown fat cells and enhances their heat-generating capacity in female mice. The findings reveal a female-specific mechanism of energy metabolism, boosted by PGC-1α and estrogen, which could inspire new therapies for the prevention of obesity and diabetes.
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AI detects subtle movement changes in finger-tapping videos, revealing hidden Parkinson’s signs

Early detection of even the slightest motor function changes can be critical to slowing the progression of Parkinson’s disease. Yet these subtle signs often go unnoticed. Now, UF researcher Diego L. Guarín, Ph.D., is harnessing AI to spot these subtle changes from video recordings before clinical symptoms become evident to the clinician’s eyes.
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Green tea improves insulin sensitivity and glucose tolerance in obese mice

Green tea is an ancient beverage recognized for its medicinal and antioxidant properties. It has been widely studied for its beneficial effects on metabolic diseases, such as obesity and type 2 diabetes. Recent studies have deepened our understanding of the mechanisms of action of this infusion and revealed that green tea treatment reduced weight and significantly improved glucose sensitivity and insulin resistance in obese mice. These results reinforce the potential relevance of the beverage as an adjunct in the treatment of obesity in humans.
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Media visibility and costs of new medicines under examination—what does the media highlight?

A study conducted by the University of Eastern Finland and Fimea found that the Finnish news media has given GLP-1 agonists used to treat obesity, such as semaglutide, a great deal of attention while many other new medicines have been ignored. Based on preliminary results, media visibility is not evenly divided between medicines intended for different indications, and the amount of visibility does not always correspond to such things as the user-specific costs of medicines or the prevalence of indications.
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