Per- and polyfluoroalkyl substances (PFAS), manmade chemicals that accumulate in the body over time, have been linked to liver disease and cancer, but it is not yet clear how they cause damage. Researchers from the Keck School of Medicine of USC have used a lab model of the human liver to analyze changes at the cellular level, finding that some PFAS triggered fat accumulation and others caused cell damage linked to cancer.

Children with a rare, debilitating muscle disease could benefit from the findings of new research by experts at UCL and Great Ormond Street Hospital (GOSH).

New research from the University of Minnesota Medical School is providing important insights into how COVID-19 persists in cancer patients even long after testing positive. The findings were recently published in iScience.

An international multidisciplinary team has demonstrated for the first time that CRISPR-based gene activation (CRISPRa) can be used to treat genetic heart disease in vivo. The study, published in the European Heart Journal and presented at the European Society of Cardiology Congress in Madrid, paves the way for novel targeted therapies for patients with genetic cardiac disorders. This approach could be especially useful for patients with conditions caused by mutations in genes too large to be targeted with conventional gene therapy.