MyBlueDots

A pathological partnership between Salmonella and yeast in the gut

University of Illinois Chicago-led researchers have found that a common gut yeast, Candida albicans, can help Salmonella Typhimurium take hold in the intestine and spread through the body. When interacting, a Salmonella protein called SopB prompts the yeast to release arginine, which turns on Salmonella’s invasion machinery and quiets the body’s inflammation signals.
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Using deep learning for precision cancer therapy

Nearly 50 new cancer therapies are approved every year. This is good news. “But for patients and their treating physicians, it is becoming increasingly difficult to keep track and to select the treatment methods from which the people affected—each with their very individual tumor characteristics—will benefit the most,” says Dr. Altuna Akalin, head of the Bioinformatics and Omics Data Science technology platform at the Berlin Institute for Medical Systems Biology of the Max Delbrück Center (MDC-BIMSB).
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Novel PET tracer detects synaptic changes in spinal cord and brain after spinal cord injury

A new PET tracer can provide insights into how spinal cord injuries affect not only the spinal cord, but also the brain, according to new research published in The Journal of Nuclear Medicine. By identifying synapse loss, the PET approach provides molecularly unique and complementary information to other structural imaging methods, offering a promising objective metric to evaluate novel therapeutics for spinal cord injuries.
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