Common pregnancy complications may be signals of future stroke risk
Women who experience complications during pregnancy face a higher risk of stroke in the following decades, according to research published in the European Heart Journal.
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Phase III trial shows gene therapy skin grafts help heal chronic wounds in blistering skin disease
Skin grafts genetically engineered from a patient’s own cells can heal persistent wounds in people with an extremely painful dermatologic disease, a Stanford Medicine-led clinical trial has shown. The grafts treat severe dystrophic epidermolysis bullosa, or EB, a genetic condition in which the skin is so fragile the slightest touch can cause blistering and wounds, eventually leading to large, open lesions that never heal and are immensely painful.
‘Pill-on-a-thread’ could replace endoscopies for half of all patients being monitored for esophageal cancer risk
Endoscopies could be replaced by far less invasive capsule sponge tests for half of all patients with Barrett’s esophagus, a known precursor to esophageal cancer, according to a new study by researchers at the University of Cambridge, Addenbrooke’s Hospital and Queen Mary University of London. The research was published in The Lancet.
Zoning out could be beneficial—and may actually help us learn faster
Aimlessly wandering around a city or exploring the new mall may seem unproductive, but new research from HHMI’s Janelia Research Campus suggests it could play an important role in how our brains learn.
Heart valve for young children shines in early-stage preclinical testing
Researchers at the University of California, Irvine have successfully performed preclinical laboratory testing of a replacement heart valve intended for toddlers and young children with congenital cardiac defects, a key step toward obtaining approval for human use. The results of their study were published recently in the Journal of the American Heart Association.
Macrophages elicit separate pathways for inflammation and lysosomal function in diseases due to toxic particle exposure
Human exposure to toxic particles drives various diseases. Examples include gout, an acute arthritis driven by monosodium urate crystals, or MSUc; CPPD disease, another inflammatory joint disease driven by calcium pyrophosphate dihydrate crystals, or CPPDc; and the lung disease silicosis, driven by inhaled silica-derived nanoparticles.
Weekly semaglutide improves blood sugar and weight in adults with type 1 diabetes, clinical trial finds
A new clinical trial found that taking a popular diabetes and weight-loss drug once weekly significantly improves blood sugar and leads to substantial weight loss in adults with type 1 diabetes who use automated insulin delivery systems.
AI chatbot safeguards fail to prevent spread of health disinformation, study reveals
A study assessed the effectiveness of safeguards in foundational large language models (LLMs) to protect against malicious instruction that could turn them into tools for spreading disinformation, or the deliberate creation and dissemination of false information with the intent to harm.
FDA approves Monjuvi for relapsed, refractory follicular lymphoma
The U.S. Food and Drug Administration has approved Monjuvi (tafasitamab-cxix) for the treatment of adult patients with relapsed or refractory follicular lymphoma.
Dual-targeting radiopharmaceutical therapy safe and effective across multiple cancers
A new cancer treatment that delivers radiation directly to tumors by targeting two key markers simultaneously has been shown to be safe and effective in human trials. Acting like a “smart missile,” the dual-targeting radiopharmaceutical is designed to attach to two vulnerable sites on cancer cells, enabling more precise and potent therapy. Early results show that nearly 90% of patients experienced either tumor shrinkage or disease stabilization. These findings were presented at the Society of Nuclear Medicine and Molecular Imaging 2025 Annual Meeting.