Arthritis & Rheumatism

Social determinants of health (SDH), such as socioeconomic status and educational background are factors that are increasingly recognized as critical contributors to health outcomes in chronic diseases. Understanding how certain factors impact different rheumatic and musculoskeletal diseases (RMDs) is important, and new research into this for both systemic lupus erythematosus (SLE) and inflammatory arthritis was presented at the EULAR 2025 congress in Barcelona.

The Very Early Diagnosis of Systemic Sclerosis (VEDOSS) criteria identify red flags as puffy fingers, abnormal nailfold capillaroscopy, and specific autoantibodies in patients with Raynaud’s phenomenon as a very early disease stage where patients do fulfill the classification criteria.

Osteoarthritis (OA) is one of the most prevalent conditions affecting tens of millions of U.S. adults, traditionally understood as a disease driven primarily by mechanical wear and tear. This perspective is being reshaped by emerging research that highlights the contribution of metabolic pathways to OA development and progression.

Exercise therapy is suggested as a first-line treatment to improve joint pain and loss of function caused by osteoarthritis (OA), a musculoskeletal disorder that affects more than 595 million people worldwide. Yoga and strengthening exercises are both known to be effective ways of managing knee OA, but is one better than the other?

A clinical trial co-led by the Hospital for Special Surgery (HSS) has found that blocking inflammation with the drug certolizumab significantly reduces the risk of serious adverse pregnancy outcomes in women with antiphospholipid syndrome (APS).

Delays in diagnosing and treating psoriatic arthritis—a common inflammatory disorder affecting around 200,000 people in the U.K.—are causing irreparable damage to people’s health. This damage could be avoided by catching the condition earlier and treating it effectively, according to research led by scientists in the Department of Life Sciences at the University of Bath.

Intermittent fasting may benefit antioxidant and inflammatory markers in postmenopausal women with rheumatoid arthritis, according to a study published online Jan. 18 in Scientific Reports.