Synergistic drug combinations explored for systemic sclerosis vasodilation

It is known that vasculopathy plays a pivotal role in the pathogenesis of systemic sclerosis (SSc). Vasoactive vasodilating drugs (VVD) are an option. The most recent treatment recommendations from EULAR—The European Alliance of Associations for Rheumatology—note that advances in vasculopathy management for patients with SSc emphasize a treatment continuum for the use of various VVD, but also stress the need for trials to look for potential synergistic combinations as well as high-quality real-world data to build the evidence. New data shared at the 2025 EULAR congress in Barcelona may take a step in that direction.
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Heart disease and diabetes drive surge in deaths among Americans without college degrees

About 525,000 more deaths occurred among US adults in 2023 than would be expected had pre-2010 mortality trends continued. More than 90% of these deaths occurred among individuals without a bachelor’s degree and were largely caused by cardiovascular diseases, underscoring how educational attainment can influence individuals’ health opportunities and outcomes.
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Online education on atrial fibrillation can enhance clinical guideline use by more than 50%

An international study has shown that targeted online education on atrial fibrillation (AF) for health professionals can improve guideline-adherent care. This cluster-randomized controlled trial, published in Nature Medicine this week, was designed to test if structured online AF education for health professionals could improve the care that individual patients receive.
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Increasing numbers of US adults don’t know they have diabetes, high blood pressure or high cholesterol

In a new report published in JAMA Cardiology, health policy experts at the Richard A. and Susan F. Smith Center for Outcomes Research at Beth Israel Deaconess Medical Center (BIDMC) have shown that many US adults are unaware they have high blood pressure, diabetes and high cholesterol—three major risk factors for cardiovascular disease and death.
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