How alcohol opens the floodgates for harmful bacteria to reach the liver

Alcohol-associated liver disease (ALD) is a major cause of liver transplantation and death worldwide, and its impact is only growing. In 2022, the annual cost of ALD in the United States was $31 billion. By 2040, this number could be as high as $66 billion. ALD has limited therapeutic options, so scientists are looking for new ways to target the molecular biology of ALD to help prevent its occurrence or reduce its severity.
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Mini-organ models reveal hantavirus secrets, point to treatments

UCLA researchers have created miniature stem cell-based organoid models of human lungs, hearts and brains to study how hantaviruses—rare but often deadly viruses spread by rodents—infect the body. Hantaviruses were thrust into the national spotlight earlier this year as the cause of death for Betsy Arakawa, the classical pianist and wife of late actor Gene Hackman.
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