Diseases, Conditions, Syndromes

A team of scientists led by the A*STAR Genome Institute of Singapore (A*STAR GIS) have released one of the world’s largest and most comprehensive long-read RNA sequencing datasets, addressing a long-standing bottleneck in disease research.

UC Davis Health’s first-of-its-kind total body scanner EXPLORER is being given yet another new assignment—assessing how cancer, neurodegenerative diseases and other systemic conditions, can affect the brain.

Hepatitis D virus (HDV) infects the liver and causes severe inflammation. According to WHO estimates, 12 million people worldwide are infected with HDV. Currently, there are only a few treatment options.

Compromised antigen presentation ranks among the top mechanisms that render cancers non-immunogenic (non-responsive to immune-based therapies). Despite harboring the highest tumor mutational burden of all cancers, basal cell carcinomas (BCCs) have low immunogenicity.

Long COVID can result in increased risk for a variety of serious health problems for young people, including those affecting the kidney, gut, and cardiovascular system, according to a group of new studies led by investigators at the Perelman School of Medicine at the University of Pennsylvania.

Montana is the ninth U.S. state to have an active measles outbreak.

Primary progressive aphasia is a neurological condition that causes a gradual decline in language abilities. There is no cure or medication that can reverse or stop the progression of PPA. The standard practice in the clinical setting is speech-language therapy to help people with PPA maintain their ability to communicate.

Anemia, a condition marked by low levels of hemoglobin in the blood, affects nearly 2 billion people worldwide. Among them, school-age children in low- and middle-income countries are particularly vulnerable. Left untreated, anemia in children can interfere with growth, learning, and overall development. Detecting the condition early is essential, but standard diagnostic methods require blood samples and lab equipment—resources that are often unavailable in low-income areas.

Key labs at the U.S. Centers for Disease Control and Prevention (CDC) have shut down amid recent layoffs, raising concerns about tracking and controlling serious infections like viral hepatitis and antibiotic-resistant gonorrhea.

Key labs at the U.S. Centers for Disease Control and Prevention (CDC) have shut down amid recent layoffs, raising concerns about tracking and controlling serious infections like viral hepatitis and antibiotic-resistant gonorrhea.