Immune ‘fingerprints’ aid diagnosis of complex diseases

Your immune system harbors a lifetime’s worth of information about threats it’s encountered—a biological Rolodex of baddies. Often the perpetrators are viruses and bacteria you’ve conquered; others are undercover agents like vaccines given to trigger protective immune responses or even red herrings in the form of healthy tissue caught in immunological crossfire.
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Advances in corneal healing research drive new treatments for rare eye diseases

Rare eye diseases are the leading cause of untreatable blindness in Europe and affect people of all ages. The RESTORE VISION scientific team has identified seven rare ocular conditions that impact the cornea and the rest of the ocular surface. “With a comprehensive approach, we aim to restore the normal function of the immune, vascular, and nervous systems of the ocular surface by studying existing drugs while also developing new, accessible treatments,” says Juana Gallar, a professor at UMH who leads the project and the Ocular Neurobiology Laboratory at the IN.
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Herpesviruses may contribute to Alzheimer’s disease via transposable elements

Researchers from Cleveland Clinic’s Genome Center have outlined the pathway human herpes simplex virus-1 (HSV1) can use to contribute to Alzheimer’s disease in aging brains. In a report published in Alzheimer’s & Dementia, investigators also share two FDA-approved, commercially available drugs that reverse this pathway in a laboratory setting.
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Managing the next pandemic: Staggering stay-at-home orders proven to be effective

A study recently published in Management Science examines the impact of stay-at-home orders implemented by U.S. counties in the early stages of the COVID-19 pandemic. Conducted by economists at Johns Hopkins Carey Business School, the research reveals that SHOs not only reduced mobility in counties where they were implemented but also had significant “spillover effects” in neighboring counties.
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