Immunology

A new study published in The Journal of Immunology reveals how a high-fat diet may impair the immune system’s ability to respond to infection by impacting the function of neutrophils, one of the first immune cells to respond to bacteria or viruses.

Antibodies, which recognize viruses and proteins that the body has encountered before, have long gotten most of the credit for giving the human immune system a memory. Now, researchers at the University of Chicago Pritzker School of Molecular Engineering have discovered a new form of immune memory.

A single molecular switch is essential for blood stem cells to enter an activated, regenerative state in which they produce new blood cells, according to a preclinical study led by Weill Cornell Medicine investigators. The discovery could lead to more effective bone marrow transplants and gene therapies.

New research suggests that receiving multiple doses of a vaccine in the same limb leads to faster antibody development, an important strategy for providing immunity as quickly as possible during a pandemic or disease outbreak.

Spring brings warmer weather, but for allergy sufferers, it also means sneezing, wheezing and itchy eyes. Instead of enjoying the season, you may be battling congestion and brain fog. So, what can you do to manage your spring allergy symptoms?

A clinical trial has found that the medication omalizumab, marketed as Xolair, treated multi-food allergy more effectively than oral immunotherapy (OIT) in people with allergic reactions to very small amounts of common food allergens.

New research reveals insight into the impact sleep quality has on a person’s immune system, and how it could be linked to the development of diseases such as obesity, diabetes, and cardiovascular diseases.

Stanford University researchers developed a machine learning-based method capable of diagnosing multiple diseases using B cell and T cell receptor sequences. The model, called Machine learning for Immunological Diagnosis (Mal-ID), distinguished between COVID-19, HIV, lupus, type 1 diabetes, influenza vaccination response, and healthy states, achieving near-perfect classification.

Valentine’s Day isn’t just about gifts—it’s about showing your special someone you truly care.

Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders—T cells—lose their ability to function effectively. Research, led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute) and the Peter MacCallum Cancer Center (Peter Mac), have identified a rare type of immune cells, called stem-like T cells, that holds the key to maintaining powerful, long-term immune responses.