Inflammatory disorders

Ulcerative colitis (UC) causes misery for millions worldwide. It affects the large intestine, causing pain, cramping, and frequent bowel movements with bloody diarrhea. Although some people go through periods when they feel well, the disease will suddenly flare up, causing another cycle of pain, diarrhea, and weight loss. There is currently no cure.

What can lemurs tell us about inflammation and aging, aka “inflammaging” in humans? That’s the question Elaine Guevara, a biological anthropologist who studies the evolution of life history and aging in primates, set out to understand.

What can lemurs tell us about inflammation and aging, aka “inflammaging” in humans? That’s the question Elaine Guevara, a biological anthropologist who studies the evolution of life history and aging in primates, set out to understand.

Cashew is an increasingly relevant allergen leading to anaphylaxis in children, according to a study published online June 13 in Allergy.

Chronic wounds are a major medical challenge, burdening health care systems with billions of dollars in costs every year. Pioneer Fellow Börte Emiroglu is developing a new product: a selective, sponge-like hydrogel that reduces inflammatory signals and actively promotes healing.

Skin grafts genetically engineered from a patient’s own cells can heal persistent wounds in people with an extremely painful dermatologic disease, a Stanford Medicine-led clinical trial has shown. The grafts treat severe dystrophic epidermolysis bullosa, or EB, a genetic condition in which the skin is so fragile the slightest touch can cause blistering and wounds, eventually leading to large, open lesions that never heal and are immensely painful.

Women who work nightshifts are more likely to suffer with moderate or severe asthma compared to women who work in the daytime, according to a study published in ERJ Open Research.

Be it peanuts or other triggers, many families live with the day-to-day risk that their child might experience a sudden and scary allergic reaction. Pediatric emergency department visits in the United States to treat acute allergic reactions more than tripled from 2008 to 2016.

New findings from the Barwon Infant Study show the pattern of gene activity in babies’ noses is strongly linked to their risk of subsequent wheezing illnesses.

A new study conducted by researchers at National Jewish Health has found that early changes in the cheek skin barrier may predict the onset of eczema, or atopic dermatitis (AD), well before any clinical symptoms appear. AD can be linked to food allergies, with early skin reactions potentially increasing the risk of developing asthma later in life.