Medical research

Glioblastoma (GBM), one of the most aggressive types of brain cancer, is one of the greatest challenges for medicine, both because it is difficult to treat and because of its high mortality rate. In Brazil, although no exact figures are available, it is estimated that between 10,000 and 12,000 new cases are diagnosed every year.

An international group of researchers has identified an important mechanism that enables stem cells to evade immune rejection. Their research, published in Nature, sheds light on how these specialized cells create an “immune-privileged” environment—areas in the body where stem cells survive and function without being attacked by the immune system. The team was led by Kazuhiro Furuhashi (Nagoya University and Columbia University) and Joji Fujisaki (Harvard University and Columbia University).

Black Americans are more willing to participate in medical studies led by Black doctors and researchers, perceiving them as more trustworthy, finds a new study co-authored by a Cornell economist.

Following an injury, such as a traumatic crush injury, the peripheral nervous system is itself often able to effectively regenerate. This regeneration capacity is mainly attributable to the Schwann cells of the peripheral nervous system. These cells are quick-change artists that can transform themselves into repair cells when needed.

Adult human hearts possess limited regenerative abilities, so losing cardiomyocytes (CMs) after injury can result in contractile dysfunction and heart failure. In contrast, neonatal mammalian hearts can regenerate, though the underlying molecular mechanisms remain unclear.

Three people with a muscle-destroying disease destined to worsen got a little stronger—able to stand and walk more easily—when an implanted device zapped their spinal cord.

Pharmaceutical ads are difficult to avoid in American television programming and a growing number of them promote a class of medications called JAK inhibitors, using an acronym that assumes the average TV watcher knows exactly what JAK stands for.

Mitochondria are essential for generating energy that fuels cells and helps them function.

Our biceps and our brain cells may have more in common than previously thought.

A research team affiliated with UNIST has unveiled an innovative technology to eliminate drug-resistant cancer cells using light. Professors Tae-Hyuk Kwon and Duyoung Min from the Department of Chemistry at UNIST, alongside Professor Taiho Park from POSTECH, have created a photoreactive compound capable of suppressing autophagy in cancer cells—one of the key mechanisms contributing to resistance against anticancer therapies.