T cells take up residence in the healthy brain via a gut-fat-brain axis

The brain is a unique place. It is shielded from much of the body by the blood-brain barrier, meaning it’s protected from pathogens and potentially dangerous substances that might be in our blood. And historically, many scientists believed that separation extended to the immune system as well: the brain has its own specialized immune cells called microglia, but immune cells present in the rest of the body were long thought to steer clear of the brain unless there was a disease or other problem requiring their presence.
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Scientists uncover sex differences in recalling and reporting of family history of Alzheimer’s disease

Investigators in the Yale Department of Psychiatry demonstrated that females and males report different information regarding the family history of Alzheimer’s disease. In particular, the scientists observed that socioeconomic factors and cognitive abilities contribute to altering the assessment of family history of Alzheimer’s disease in large-scale studies.
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Machine learning algorithm brings long-read sequencing to the clinic

Long-read sequencing technologies analyze long, continuous stretches of DNA. These methods have the potential to improve researchers’ ability to detect complex genetic alterations in cancer genomes. However, the complex structure of cancer genomes means that standard analysis tools, including existing methods specifically developed to analyze long-read sequencing data, often fall short, leading to false-positive results and unreliable interpretations of the data.
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