MyBlueDots

High birth weight found to be leading risk factor for severe birth injury

MyBlueDots2 months ago01 mins

High birth weight is the main risk factor for birth injuries to the anal sphincter muscles of the person giving birth, according to a study at the University of Gothenburg. This new method for predicting the risks could improve care and reduce injuries.

First salivary gland regenerative biobank developed to combat chronic dry mouth

MyBlueDots2 months ago01 mins

Millions of people are affected by chronic dry mouth, or xerostomia, an agonizing side effect of damaged salivary glands. While chemotherapy and radiation treatment for head and neck cancer are the most common causes of this, aging, certain medications and other factors, including diabetes, stroke, Alzheimer’s disease and HIV/AIDS, can also cause chronic dry mouth. Currently, there is no cure for it.

Small molecules in plant-based foods may reduce efficacy of anti-cancer drugs

MyBlueDots2 months ago01 mins

A Ludwig Cancer Research study has uncovered a surprising link between diet, intestinal microbes and the efficacy of cancer therapy.

Effects of blood pressure management on cardiovascular health vary across education levels

MyBlueDots2 months ago01 mins

The effects of intensive blood pressure⁠ management on rates of cardiovascular events and death vary substantially across individuals’ levels of educational attainment, according to a new study by researchers at the University of Pittsburgh Schools of the Health Sciences and University of Texas at Tyler.

‘Fast-fail’ AI blood test could steer patients with pancreatic cancer away from ineffective therapies

MyBlueDots2 months ago01 mins

An artificial intelligence technique for detecting DNA fragments shed by tumors and circulating in a patient’s blood, developed by Johns Hopkins Kimmel Cancer Center investigators, could help clinicians more quickly identify and determine if pancreatic cancer therapies are working.

AI-powered framework can predict the evolutionary fitness of SARS-CoV-2 variants

MyBlueDots2 months ago01 mins

Viral infectious diseases pose significant challenges due to the rapid evolution of viruses through mutations. This was particularly evident during the COVID-19 pandemic, when emerging variants of SARS-CoV-2 sparked new waves of infection. These variants often carry mutations that make them more transmissible, allowing them to spread rapidly across populations.

Pulmonary fibrosis: Nerandomilast inhibits phosphodiesterase 4B, may treat multiple forms of disease

MyBlueDots2 months ago01 mins

A new drug for pulmonary fibrosis has reduced disease progression by more than 50% over a 52-week treatment in two clinical trials. Pulmonary fibrosis is a very serious disease, with a life prognosis of 3 to 5 years after diagnosis. But the new drug, nerandomilast (Boehringer Ingelheim), could revolutionize the treatment of the disease after several failures of all potential new drugs tested for this disease in the last decade that have failed in phase 2 or phase 3 studies.

Promising results of niraparib appear in patients with advanced melanoma

MyBlueDots2 months ago01 mins

Researchers at Sutter’s California Pacific Medical Center (CPMC) in San Francisco, Calif. have discovered early signs of clinical benefit while testing niraparib, a PARP inhibitor, in patients with advanced melanoma whose tumors had specific genetic changes impacting DNA repair.

Social and economic welfare policies can influence depression risk, finds research

MyBlueDots2 months ago01 mins

Policies that impact social determinants of health may influence an individual’s risk of depression, according to a new study published in PLOS One by Mary Nicolaou of the Amsterdam UMC, The Netherlands, and colleagues.

Social media fad of nighttime mouth taping to treat mouth breathing may pose serious risks

MyBlueDots2 months ago01 mins

An evaluation of 10 previously published studies suggests that a recent fad of taping one’s mouth shut while sleeping to prevent mouth breathing may have little benefit and could pose serious asphyxiation risks. Dr. Brian Rotenberg of Western University in London, Ontario, Canada, and colleagues present these findings in PLOS One.

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High birth weight found to be leading risk factor for severe birth injury

First salivary gland regenerative biobank developed to combat chronic dry mouth

Small molecules in plant-based foods may reduce efficacy of anti-cancer drugs

Effects of blood pressure management on cardiovascular health vary across education levels

‘Fast-fail’ AI blood test could steer patients with pancreatic cancer away from ineffective therapies

AI-powered framework can predict the evolutionary fitness of SARS-CoV-2 variants

Pulmonary fibrosis: Nerandomilast inhibits phosphodiesterase 4B, may treat multiple forms of disease

Promising results of niraparib appear in patients with advanced melanoma

Social and economic welfare policies can influence depression risk, finds research

Social media fad of nighttime mouth taping to treat mouth breathing may pose serious risks

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