A brief history of federal funding for basic science
Biomedical science in the United States is at a crossroads.
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Researchers develop recommendations to improve neonatology staffing
Staffing challenges related to patient safety, physician well-being and workforce sustainability are a growing concern in the subspecialty of neonatology that call for reform.
Inflammation in reproductive tract linked to infertility, hormone therapy may help
Inflammation in the female reproductive tract may make it difficult to conceive a child, but replenishing a key hormone could keep inflammation in check, according to researchers from the University of Missouri School of Medicine.
Low-cost blood test can measure proteins for early Alzheimer’s detection
Researchers from the Keck School of Medicine of USC have developed a blood test that can identify early signs of Alzheimer’s disease by measuring proteins linked to the condition. The new test, known as Penta-Plex Alzheimer’s Disease Capture Sandwich Immunoassay (5ADCSI), detects five biomarkers simultaneously, which is more than existing blood tests and runs on equipment commonly used in many laboratories.
Type 2 diabetes and brain health are linked in older adults from various populations
A new USC-led study has uncovered a significant link between type 2 diabetes mellitus and cortical thickness in older adults from various populations.
Two HIV vaccine trials show proof of concept for pathway to broadly neutralizing antibodies
A decades-long scientific challenge in HIV vaccine development has been finding a way to train the immune system to produce antibodies that can target many variants of the virus. Traditional approaches haven’t worked—largely because HIV mutates rapidly and hides key parts of itself from the immune system.
Link between ADHD and obesity might depend on where you live
Attention-deficit/hyperactivity disorder (ADHD) might contribute to obesity by reducing physical activity—a relationship that can also be mediated by the features of the urban environment in which a person lives.
Early-stage HIV vaccine triggers targeted immune response in human trial
Worldwide, an estimated 40 million people live with HIV. Two-thirds of this group are on the African continent. In 2023, more than 600,000 people died from HIV-related causes and 1.32 million were infected. There is no vaccine against the world’s second most deadly infection, after TB. However, researchers from Amsterdam UMC have set an important first step in reaching that goal. The results of their phase one trial are published in Science.
Enzyme HDAC1 found to suppress tumor growth in aggressive T-cell lymphomas
Lymphomas belong to the group of malignant diseases of the immune system and mainly affect the organs of the lymphatic system. Anaplastic large cell lymphoma (ALCL) belongs to the subgroup of non-Hodgkin’s lymphomas and is a rare but aggressive form of T-cell lymphoma that usually occurs in children and young adults.
Thetis cells identified as key player in childhood food allergies
A decade ago, a clinical trial in the U.K. famously showed that children who were exposed to peanuts in the early months of life had reduced risk of developing a peanut allergy compared with children who avoided peanuts.