Alzheimer’s disease research offers hope for finding therapeutic target that stops progression

In searching for a possible therapeutic target to stop the progress of this disease, an international scientific team, led by researchers at the Department of Cell Biology, Genetics and Physiology of the UMA and also members of the Baglietto lab and the NeuroAD research group, has identified different factors involved in the propagation processes.
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Alzheimer’s disease research offers hope for finding therapeutic target that stops progression

In searching for a possible therapeutic target to stop the progress of this disease, an international scientific team, led by researchers at the Department of Cell Biology, Genetics and Physiology of the UMA and also members of the Baglietto lab and the NeuroAD research group, has identified different factors involved in the propagation processes.
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Early mitochondrial impairment and myelin loss tied to multiple sclerosis brain damage

Multiple sclerosis (MS) affects an estimated 2.3 million people worldwide. Approximately 80% of people with MS have inflammation in the cerebellum, the part of the brain that helps control movement and balance, potentially leading to tremors, poor coordination, and trouble with motor control. These problems often persist and can worsen over time, as the cerebellum gradually loses healthy brain tissue.
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Glial replacement therapy slows Huntington’s disease in adult mice

Huntington’s disease has long defied attempts to rescue suffering neurons. A new study in Cell Reports shows that transplanting healthy human glial progenitor cells into the brains of adult animal models of the disease not only slowed motor and cognitive decline but also extended lifespan. These findings shift our understanding of Huntington’s pathology and open a potential path to cell-based therapies in adults already showing symptoms.
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Neighborly help in the brain: Cerebral cortex networks rapidly reorganize to compensate for lost neurons

How the brain largely maintains its function when neurons are lost—this is what researchers at the University Medical Center Mainz, the Frankfurt Institute for Advanced Studies (FIAS) and Hebrew University (Jerusalem) have deciphered. They show that neuronal networks in the cerebral cortex reorganize within a short period of time, with other nerve cells taking over the tasks of the lost neurons.
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