Neuroscience

A novel PET imaging approach has revealed distinct patterns of brain inflammation in patients with progressive apraxia of speech (PAOS), a rare neurodegenerative disorder that affects speech planning. These findings provide new insight into how neuroinflammation and tau pathology may drive disease progression in PAOS, opening potential avenues for earlier diagnosis and targeted treatments.

The combination of cochlear endolymphatic hydrops (CEH) and vestibular endolymphatic hydrops (VEH) on magnetic resonance imaging (MRI) accurately diagnoses Meniere disease (MD) and vestibular migraine (VM), according to a study published online May 13 in Frontiers in Neurology.

Although we know sleep is essential to our physical and mental well-being, it remains an incredibly enigmatic behavior, scientifically speaking. Researchers at the University of Michigan, however, may have developed a new hypothesis to account for one of sleep’s looming mysteries.

A paper published in the Cochrane Database of Systematic Reviews has found that virtual reality (VR), when used in addition to standard therapy, can help stroke survivors regain arm movement. The findings suggest that VR could be a promising tool to boost rehabilitation efforts, particularly by increasing the amount of therapy patients receive.

In searching for a possible therapeutic target to stop the progress of this disease, an international scientific team, led by researchers at the Department of Cell Biology, Genetics and Physiology of the UMA and also members of the Baglietto lab and the NeuroAD research group, has identified different factors involved in the propagation processes.

In searching for a possible therapeutic target to stop the progress of this disease, an international scientific team, led by researchers at the Department of Cell Biology, Genetics and Physiology of the UMA and also members of the Baglietto lab and the NeuroAD research group, has identified different factors involved in the propagation processes.

If the idea of going to the gym makes you moan and groan, you’re not alone.

Multiple sclerosis (MS) affects an estimated 2.3 million people worldwide. Approximately 80% of people with MS have inflammation in the cerebellum, the part of the brain that helps control movement and balance, potentially leading to tremors, poor coordination, and trouble with motor control. These problems often persist and can worsen over time, as the cerebellum gradually loses healthy brain tissue.

Huntington’s disease has long defied attempts to rescue suffering neurons. A new study in Cell Reports shows that transplanting healthy human glial progenitor cells into the brains of adult animal models of the disease not only slowed motor and cognitive decline but also extended lifespan. These findings shift our understanding of Huntington’s pathology and open a potential path to cell-based therapies in adults already showing symptoms.

An ETH spin-off, Swiss Vascular, has developed anatomically exact silicone models of cerebral vessels. Through this development, researchers will not only reduce the amount of animal experimentation required but also improve the standard of medical training for complex medical procedures.