Oncology & Cancer

A team of researchers from Moffitt Cancer Center has found new insight into why some lung cancer patients do not benefit from tumor-infiltrating lymphocyte, or TIL therapy. Their findings, published in Nature Cancer, may help improve future ways to deliver this cellular immunotherapy for metastatic non-small cell lung cancer.

It’s natural to feel a wave of anxiety following a diagnosis of breast cancer.

Investigators of the Vall d’Hebron Institute of Oncology’s (VHIO) Radiomics Group, led by Raquel Perez-Lopez, have developed SALSA (System for Automatic Liver tumor Segmentation And detection), a fully automated deep learning-driven tool for the precise and completely automated detection and monitoring of liver tumors (hepatocellular carcinoma). Results of this work have been published in Cell Reports Medicine.

Scientists at the Icahn School of Medicine at Mount Sinai have discovered a possible reason why some cases of melanoma—a dangerous form of skin cancer—spread to the brain. Their study, published in Molecular Cell, highlights the role of a group of proteins called the PBAF chromatin remodeling complex in keeping melanoma from getting worse.

A new liquid biopsy approach developed by Johns Hopkins Kimmel Cancer Center investigators could revolutionize brain cancer detection by identifying circulating DNA fragments from tumors and immune cells in blood samples, potentially enabling earlier diagnosis.

Researchers in Japan have developed a predictive model that could improve treatment decisions for advanced pancreatic cancer patients. By combining tumor marker readings with patients’ genetic information, their model predicts patient survival outcomes with greater accuracy and better identifies candidates who would benefit from surgery.

At 71, Tina Knowles—the fashion designer, businesswoman, and mother of Beyoncé—made headlines not for her career, but for a deeply personal revelation: her breast cancer diagnosis. In 2023, a routine mammogram uncovered two tumors in her left breast, one benign and the other malignant. Diagnosed with stage 1 breast cancer, she underwent surgery and is now cancer-free.

Researchers from the Sant Pau Research Institute (IR Sant Pau), in collaboration with Sant Pau Hospital and the Josep Carreras Leukemia Research Institute, have developed an innovative CAR-T cell therapy targeting the CD30 protein (HSP-CAR30), which has shown high efficacy in patients with refractory CD30+ lymphoma.

A highly sensitive bone marrow test could double survival rates for some groups of younger adults with acute myeloid leukemia (AML) by helping doctors identify if they might relapse up to three months earlier.

A highly sensitive bone marrow test could double survival rates for some groups of younger adults with acute myeloid leukemia (AML) by helping doctors identify if they might relapse up to three months earlier.