Oncology & Cancer

Memorial Sloan Kettering Cancer Center researchers have found RNA neoantigen vaccines that generate long-lived, functional CD8+ T cells in patients with pancreatic ductal adenocarcinoma (PDAC), potentially delaying disease recurrence.

Researchers led by the University of Ulsan College of Medicine, Korea, have checked the performance of a noninvasive urinary DNA methylation test for bladder cancer diagnosis.

A patient has achieved over 18 years of remission from neuroblastoma, a type of nerve cell cancer, following treatment with chimeric antigen receptor (CAR) T cell therapy and without requiring any additional treatments. The findings are published in Nature Medicine.

Patients with localized muscle-invasive bladder cancer (MIBC) who received radiation plus the immune checkpoint inhibitors (ICIs) durvalumab (Imfinzi) and tremelimumab (Imjudo) had durable responses that allowed for bladder preservation, according to results from the IMMUNOPRESERVE clinical trial published in Clinical Cancer Research.

Pancreatic cancer is fueled by connections to the nervous system. This is reported by scientists from the German Cancer Research Center (DKFZ) and the Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM) in Nature.

A research team led by Professor Kevin Tsia, program director of the Biomedical Engineering Program under the Faculty of Engineering of the University of Hong Kong (HKU), has developed an AI-driven imaging tool that enables speedy and precise diagnosis of cancer patients, greatly enhancing the effectiveness of their medical treatment.

An investigational therapy significantly shrank lung cancer tumors that are notoriously resistant to treatment by encouraging an attack from natural killer (NK) cells in an animal model, a study led by UT Southwestern Medical Center researchers shows. The findings, published in the Journal for ImmunoTherapy of Cancer, could lead to new types of immunotherapy that rely on this novel strategy.

Several cardiovascular risk factors, such as advanced age and smoking history, are prevalent among lung cancer patients at the time of the diagnosis and increase their risk of future heart disease, according to a new study being presented at ACC’s Advancing the Cardiovascular Care of the Oncology Patient course. Comprehensive assessments are needed in this vulnerable group to improve survival outcomes and quality of care for cancer patients.

Experiencing pain may increase the odds that cancer survivors will use cigarettes and cannabis, according to a study published online in Cancer. The study also found that cigarette smoking and pain are linked to more treatment-related side effects and worse health among cancer survivors.

Every minute, 38 people are diagnosed with cancer, and 18 people die from it globally, according to the World Health Organization, and it’s estimated to increase by 77% to 35 million in 2050. But what if we could predict cancer risks before they even develop? Genetic testing helps detect cancer risks early, making it essential for cancer prevention and control.