Oncology & Cancer

New research from the Centenary Institute has found that switching off a specific protein in liver cells may help prevent the early development of liver cancer.

A cruel consequence of advanced cancer is the profound apathy many patients experience as they lose interest in once-cherished activities. This symptom is part of a syndrome called cachexia, which affects about 80% of late-stage cancer patients, leading to severe muscle wasting and weight loss that leave patients bone thin despite adequate nutrition.

New research has revealed that Schistosoma haematobium (S. haematobium), a parasitic infection affecting millions globally, can trigger cancer-related gene activity in the cervical lining, with changes becoming even more pronounced after treatment. Presented at ESCMID Global 2025, this study sheds new light on how this often-overlooked parasitic disease may contribute to cervical cancer risk at the molecular level.

Researchers at Moffitt Cancer Center have found that tapping into the body’s own immune system and activating a type of immune cell known as B cells, could be the key to boosting the effectiveness of tumor-infiltrating lymphocyte, or TIL therapy. Results of their study were published in the Journal for Immunotherapy of Cancer.

Treatment resistance and relapse in the most common type of lung cancer can be traced to a protein called agrin, according to a preclinical study led by Roswell Park Comprehensive Cancer Center. Results of the study, led by Sayan Chakraborty, Ph.D., Assistant Professor of Oncology, Department of Pharmacology & Therapeutics at Roswell Park, have been published in the journal Advanced Science.

New research published in the Journal of Magnetic Resonance Imaging has uncovered changes in brain connectivity during chemotherapy in patients with breast cancer.

Immune checkpoint inhibitors, a class of immunotherapies that help immune cells attack cancer more effectively, have revolutionized cancer treatment. However, fewer than 20% of patients respond to these treatments, highlighting the urgent need for new strategies tailored to both responders and non-responders.

Researchers at National Taiwan University Hospital (NTUH) have uncovered a concerning rise in high-risk colorectal neoplasms—growths that can lead to colorectal cancer—among younger adults in Taiwan. Their findings suggest it may be time to reconsider when to begin routine colorectal cancer screenings.

A team of researchers from the Rice Biotech Launch Pad at Rice University has developed an implantable “cytokine factory” that safely triggers potent immune responses against hard-to-treat cancers, including metastatic melanoma, pancreatic and colorectal tumors.

In a new study, researchers from Huntsman Cancer Institute at the University of Utah (the U) found that 7% of Medicare patients cross state borders for cancer care, and rates were nearly double for those who lived in rural areas. This has important implications for telehealth policies and physician licensure, says Tracy Onega, Ph.D., MA, MPAS, MS, senior author of the study, senior director of population sciences at Huntsman Cancer Institute, and professor of population sciences at the U. A key research priority at Huntsman Cancer Institute is working to enhance access to care for cancer patients who live far from a major medical center.