Oncology & Cancer

Human Papilloma Virus (HPV) self-sampling promises to make the process of screening for cervical cancer easier, more comfortable—and, for some, less traumatic—than a traditional Pap test, offering users more control over their reproductive health.

For patients with stage IA non-small cell lung cancer (NSCLC), lung resections, including lobectomy and segmentectomy, are associated with improved long-term survival compared with wedge resection, according to a study presented at the annual meeting of The Society of Thoracic Surgeons, held from Jan. 24 to 26 in Los Angeles.

Artificial intelligence is able to identify women who have an elevated risk of developing breast cancer several years before it is diagnosed, the Norwegian Institute of Public Health (FHI) said on Tuesday.

A group led by the Department of Neurosurgery, Brain Research Institute, Niigata University, has succeeded in the diagnosis of leptomeningeal disease in diffuse midline gliomas by detecting H3K27M-mutant droplets from circulating tumor DNA of cerebrospinal fluid taken from these patients.

A person’s lifetime risk for cancer may begin before they are even born, reports a paradigm-shifting study by Van Andel Institute scientists.

Glycolysis is a central metabolic pathway by which cells obtain energy from sugar. Cancer cells in particular have long been thought to depend on the energy obtained through glycolysis, a phenomenon known as the Warburg effect. Today we know that cancer cells can use energy sources more flexibly than previously thought. Even when glycolysis is blocked, they survive by obtaining their energy through the respiratory chain.

UK oncology researchers have come together to write the first-ever national thought leadership strategy report into cancer vaccine advances and the opportunities these present for those affected by cancer. The strategy report has been published in the journal Cambridge Prisms: Precision Medicine.

Hadron therapy is a state-of-the-art radiotherapy technique that uses proton or ion beams to target tumoral cells, while sparing surrounding healthy tissues from unwanted radiation. To achieve best results, it requires complex systems, called gantries, that rotate around the patient, carrying magnets that guide the hadron beams precisely onto tumors. Unfortunately, these are usually massive and costly machines, which represent a limiting factor for the spread of the treatment technique.

A fusion protein therapy may be an effective treatment option for cutaneous T-cell lymphomas, according to a multicenter clinical trial published in the Journal of Clinical Oncology.

A new international clinical trial led by the National Cancer Center Singapore is reporting that three years of aspirin following standard adjuvant therapy for high-risk Dukes’ B and C colorectal cancer did not yield a significant advantage in preventing disease recurrence.