Oncology & Cancer

A new cancer treatment that delivers radiation directly to tumors by targeting two key markers simultaneously has been shown to be safe and effective in human trials. Acting like a “smart missile,” the dual-targeting radiopharmaceutical is designed to attach to two vulnerable sites on cancer cells, enabling more precise and potent therapy. Early results show that nearly 90% of patients experienced either tumor shrinkage or disease stabilization. These findings were presented at the Society of Nuclear Medicine and Molecular Imaging 2025 Annual Meeting.

The International Osteoporosis Foundation (IOF) Bone and Cancer Working Group has released a comprehensive review detailing the often under-recognized impact of modern anti-cancer treatments on bone health.

Using a newly discovered byproduct of dying cancer cells, University of Wisconsin–Madison researchers are developing personalized vaccines that could help keep aggressive tumors from recurring.

Altum Sequencing, a start-up supported by the C3N-IA Science Park at Universidad Carlos III de Madrid (UC3M) and specialized in oncology, has developed a tool to monitor treatment response in patients with solid tumors from a simple blood sample. This advance could represent a turning point in post-treatment follow-up.

Radioactive iodine treatment after thyroid cancer surgery usually means side effects like nausea and time in hospital isolated from loved ones. But new clinical trial results from researchers at UCL mean patients worldwide could now safely be spared this treatment.

Scientists at St. Jude Children’s Research Hospital and Dana-Farber Cancer Institute today report the identification of a novel combination therapy approach to treat pediatric acute myeloid leukemia (AML). Standard treatment is often ineffective against AML, a cancer that commonly relapses with poor prognosis, particularly when the disease is fueled by fusion proteins involving NUP98.

A Peter Mac-initiated clinical trial suggests a way to dramatically improve outcomes in patients with high-risk forms of large B-cell lymphoma, who otherwise have a 50% chance of cure from conventional therapy.

Researchers at VCU Massey Comprehensive Cancer Center have developed a novel algorithm that could provide a revolutionary tool for determining the best options for patients—both in the treatment of cancer and in the prescription of medicines.

Liver cancer is the sixth most common cancer globally and a leading cause of cancer-related deaths. Accurate segmentation of liver tumors is a crucial step for the management of the disease, but manual segmentation by radiologists is labor-intensive and often results in variations based on expertise.

Dr. Allison Rosenthal’s experience facing a leukemia diagnosis while in medical school inspired her to pursue a career fighting cancer. It also gave her insight into aspects of life with cancer for people under 40. Now, Dr. Rosenthal is among the leaders of an effort at Mayo Clinic Comprehensive Cancer Center to help younger adults and older teens receive age-appropriate care and support. In this expert alert, Dr. Rosenthal shares three topics that younger people with cancer often want to discuss with their healthcare teams.