Oncology & Cancer

The broccoli and Brussels sprouts that often get pushed to the edge of the plate might aid in reducing the risk of colon cancer.

Australian researchers have used an innovative genome-wide screening approach to identify genes, and their encoded proteins, that play critical roles in the prevention of lymphoma development, revealing new potential treatment targets for these blood cancers.

Cutting off blood flow can prematurely age the bone marrow, weakening the immune system’s ability to fight cancer, according to a new study from NYU Langone Health.

When Jesse J, Christina Applegate and Katie Thurston spoke openly about their mastectomies, their candor did more than share private struggles. It highlighted a procedure that, while often life saving, is unevenly available depending on the genetic lottery into which someone is born.

A research project has reached an important milestone: the first treatment of an animal tumor with radioactive ion beams has been demonstrated and published in Nature Physics.

A new study delving into the genetic drivers of a rare and aggressive childhood cancer called Malignant Peripheral Nerve Sheath Tumor (MPNST) has revealed metabolic frailties in the cancer cells that might be exploited to improve treatments for patients.

A study from Denmark shows for the first time that men with biochemically recurrent prostate cancer who undergo PSMA PET/CT before salvage radiotherapy have improved survival rates compared to those who do not.

NRG Oncology recently reported the results of the phase II/III NRG-BN007 clinical trial showing that combining ipilimumab and nivolumab with radiation therapy (RT) did not improve progression-free survival (PFS) for patients with newly diagnosed MGMT-unmethylated (uMGMT) glioblastoma in comparison to standard RT with temozolomide (TMZ). Accordingly, this trial will not progress to a phase III. These results were recently published in the Journal of Clinical Oncology.

A computational approach by St. Jude Children’s Research Hospital scientists promises to make designing T-cell-based immunotherapies that target two cancer-related antigens at the same time far easier and faster.

Adding a MET gene inhibitor enhances the effect of combined chemotherapy and immunotherapy in small cell lung cancer (SCLC), according to a multicenter study led by the Hospital del Mar Research Institute, in collaboration with researchers from the CIBERONC cancer research network.