Oncology & Cancer

A study conducted at the Botucatu School of Medicine at São Paulo State University (FMB-UNESP) in Brazil has shown that low-dose vitamin D supplementation can increase the effectiveness of chemotherapy treatment in women with breast cancer. The results suggest that the substance could be an alternative to hard-to-access drugs that also aim to increase the response to chemotherapy.

A combination therapy that adds a recently approved drug to the current standard of care for newly diagnosed acute myeloid leukemia (AML) showed high rates of complete remission in an early-phase clinical trial conducted at UNC Lineberger Comprehensive Cancer Center and 11 other sites nationwide.

A blood-based test has acceptable accuracy for colorectal cancer detection but not for advanced precancerous lesions in an average-risk colorectal cancer screening population, according to a study published online June 2 in the Journal of the American Medical Association.

Pancreatic cancer is a severe illness and major challenge in cancer medicine since it is difficult to diagnose, while potential therapies are scarce. A new international cooperation study indicates that in the future pancreatic cancer may be detected at an early stage from gut microbes. Gut microbes may also offer solutions for therapy development.

Scientists have discovered tumors can tap a nontraditional pathway to acquire lipoproteins—molecules that transport fat in blood—which enriches cancer cells with an antioxidant shield to survive stress, according to new research from Children’s Medical Center Research Institute at UT Southwestern (CRI) published in Nature.

A new target for potential treatments for blast phase myeloproliferative neoplasm (BP-MPN), one of the most aggressive forms of leukemia, has been identified by a research team at the University of Oxford.

Tumor cells have higher metabolic activity compared to healthy tissue and consequently consume a lot of glucose. Positron Emission Tomography (PET)—the current gold standard diagnostic technique—exploits this property.

A newly developed molecular imaging technique can identify multiple subtypes of triple-negative breast cancer (TNBC), enabling earlier and more accurate detection of this aggressive disease, according a paper published in The Journal of Nuclear Medicine titled “Targeting Extra Domain A of Fibronectin to Improve Noninvasive Detection of Triple-Negative Breast Cancer.”

Imagine diagnosing cancer not with a supercomputer but on an ordinary laptop instead. Sounds like science fiction? Thanks to a revolutionary artificial intelligence (AI) model developed by Professor Kenji Suzuki and his research team from Institute of Science Tokyo (Science Tokyo), this far-fetched scenario is now a reality.

For patients with resectable gastric or gastroesophageal junction adenocarcinoma, durvalumab plus fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) yields better event-free survival outcomes than FLOT alone, according to a study published online June 1 in the New England Journal of Medicine. The research was published to coincide with the annual meeting of the American Society of Clinical Oncology, held from May 31 to June 4 in Chicago.