Oncology & Cancer

Envision this possible future clinical scenario: a breast cancer patient and her physicians are deciding on the best possible treatment. Their decision is informed by a comprehensive molecular profile of the patient’s cancer samples that predicts the most likely response of the cancer to treatment.

Colorectal cancer screening programs are currently underutilized in Germany. This also applies to testing for blood in the stool. The immunological stool tests can detect tiny amounts of blood in the stool. Scientists at the German Cancer Research Center (DKFZ) have investigated whether smartphone-based testing could be a meaningful alternative or supplement to traditional laboratory tests. The paper is published in the journal Clinical Gastroenterology and Hepatology.

Recent results from the NRG-NSABP B-51/RTOG 1304 clinical study showed that the addition of regional nodal irradiation (RNI) does not decrease the rates of invasive breast cancer recurrence in patients whose positive axillary nodes at presentation convert to negative following neoadjuvant chemotherapy. These results were recently published in the New England Journal of Medicine.

A study led by University of Cincinnati Cancer Center researchers sheds new light on the mechanisms by which a major oncogene promotes and sustains lymphoma development and progression, paving the way for novel targeted therapies.

Young patients with cancer need support when it comes to scholastic performance, which can be an empowering and motivating force during the challenges of cancer treatment, UF Health Cancer Center researchers have found.

For U.S. adult cancer survivors with a new alcohol use disorder (AUD) diagnosis, the one-year cumulative incidence of AUD treatment initiation was 14.3%, according to a research letter published online May 27 in the Annals of Internal Medicine.

A dysfunction in muscle blood vessels could be to blame for the weak muscles and weight loss that most cancer patients experience, according to a new study from University of Illinois Chicago researchers.

Long-read sequencing technologies analyze long, continuous stretches of DNA. These methods have the potential to improve researchers’ ability to detect complex genetic alterations in cancer genomes. However, the complex structure of cancer genomes means that standard analysis tools, including existing methods specifically developed to analyze long-read sequencing data, often fall short, leading to false-positive results and unreliable interpretations of the data.

A pioneering biobattery has been shown to reduce tumor growth in the body and could hold the key to a new drug-free immunotherapy treatment in cancer patients.

Researchers have uncovered that some childhood cancers have a substantially higher number of DNA changes than previously thought, changing the way we view children’s tumors and possibly opening up new or repurposed treatment options.