Oncology & Cancer

The anti-obesity medication tirzepatide, marketed as Mounjaro for diabetes and Zepbound for obesity, reduced obesity-associated breast cancer growth in a mouse model, according to a study being presented Saturday at ENDO 2025, the Endocrine Society’s annual meeting in San Francisco, Calif.

A new study led by investigators from Mass General Brigham trialed stereotactic (targeted) brain-directed radiation in 100 patients with small cell lung cancer and brain metastases, finding they experienced positive outcomes that support use of targeted radiation in the future for such patients. Results are published in the Journal of Clinical Oncology.

People exposed to higher levels of air pollution may be more likely to develop meningioma, a typically noncancerous brain tumor, according to a large study published in Neurology. This common type of brain tumor forms in the lining of the brain and spinal cord. The findings do not prove that air pollution causes meningioma; they only show a link between the two.

Cancer does not develop overnight. It can take decades for cancer‐promoting changes in the genome to eventually lead to the formation of a malignant tumor.

Scientists at The Wistar Institute have discovered how a key protein from the Epstein-Barr virus (EBV), EBNA-LP, fundamentally rewires the three-dimensional structure of DNA in infected B cells to promote cancer development.

A research team led by Prof. Gu Hongcang and Zhang Fan from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences has identified a novel long non-coding RNA (lncRNA)-driven regulatory network that plays a central role in colorectal cancer (CRC) progression and immune response.

The herpes simplex virus type 1 (HSV-1), which affects almost two‑thirds of the world’s population and is generally associated with oral herpes, may cause painful cold sores or fever blisters around the mouth.

Talking to loved ones about a recent head and neck cancer diagnosis can be overwhelming. Of course, there is no one “right” or “wrong” way to handle these conversations—or adjusting to your life with cancer. Everyone has their own pace, preferences and relationship patterns. But taking the time to consider your approach can help make these conversations more manageable.

Drinking water treatment that pursues a multi-contaminant approach, tackling several pollutants at once, could prevent more than 50,000 lifetime cancer cases in the U.S., finds a new study by the Environmental Working Group.

Breast cancer often relapses in distant organs even when complete regression of primary tumors is achieved after initial treatment. Dormant and persistent disseminated tumor cells (DTCs) have been observed in animals with non-metastatic disease, which cannot be targeted by systemic chemotherapy.