Rare loss-of-function variants in HECTD2 and AKAP11 confer risk of bipolar disorder
Scientists at deCODE genetics/Amgen have identified associations between bipolar disorder and rare loss-of-function variants in two genes.
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Most in-depth simulation of brain metabolism yet reveals new targets for future dementia treatments
A new open-source model of brain metabolism—the most complex ever generated—has shown how altering key chemicals could restore aged cells to their youthful activity and resilience.
Chewing gum releases microplastics into mouth: researchers
Chewing gum releases hundreds of tiny plastic pieces straight into people’s mouths, researchers said on Tuesday, also warning of the pollution created by the rubber-based sweet.
Study confirms accuracy of blood test for early Alzheimer’s detection in Asian populations
A study in Alzheimer’s & Dementia has demonstrated the high accuracy of plasma p-tau217 as a blood-based biomarker for detecting abnormal brain beta-amyloid (Aβ) pathology, a hallmark of Alzheimer’s disease (AD).
Increased use of chest X-rays linked to earlier lung cancer diagnosis and improved survival
A groundbreaking study has revealed a significant link between the frequency of chest X-ray referrals from GPs and earlier diagnosis and improved survival rates for lung cancer patients.
Brain pathway may explain higher depression rates in teen girls
Depression is a mental health condition that affects 280 million people worldwide. It is twice as common in women than men and this pattern starts to develop during adolescence. Researchers have studied the biological processes that drive depression in adults and have shown a potential role for the kynurenine pathway, but this is the first time it has been investigated in adolescents in relation to biological sex.
Delay of more than 42 days for breast cancer surgery raises death risk for certain subtypes, study finds
Patients with certain subtypes of breast cancer may face a higher risk of death from the cancer if they wait more than 42 days after diagnosis to have surgery, according to newly published research from the University of Oklahoma.
Novel IVF method mimics fallopian tube environment, increasing sperm viability
The success of in vitro fertilization depends on many factors, one of which is sperm viability. A recent study from the University of Illinois Urbana-Champaign documents a new way to select viable sperm and prolong their viability in the laboratory, reducing one source of variability during the process. The work is published in the journal Scientific Reports.
Affordable sensing system enhances tactile feedback in minimally invasive surgery
Researchers from NYU Abu Dhabi’s Advanced Microfluidics and Microdevices Laboratory (AMMLab) have developed an innovative sensing system that restores the missing tactile feedback in minimally invasive surgery (MIS), enhancing precision, ease of use, and safety. The new “off-the-jaw” system integrates force and angle sensors into the handle of laparoscopic tools, providing surgeons with real-time measurements of grasping forces and insights into tissue stiffness and thickness.
Cuproptosis, a form of cell death, may link copper imbalance and atherosclerosis
Atherosclerosis (AS) is a chronic inflammatory disease characterized by the buildup of lipids and immune cells in arterial walls, increasing the risk of cardiovascular conditions. While multiple factors contribute to AS, recent research highlights the role of copper, an essential trace element, in disease progression.