Specialized blood vessels and nitric oxide found to be key to stem cell survival and immune evasion

An international group of researchers has identified an important mechanism that enables stem cells to evade immune rejection. Their research, published in Nature, sheds light on how these specialized cells create an “immune-privileged” environment—areas in the body where stem cells survive and function without being attacked by the immune system. The team was led by Kazuhiro Furuhashi (Nagoya University and Columbia University) and Joji Fujisaki (Harvard University and Columbia University).
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Novel radiotracer identifies biomarker for triple-negative breast cancer

A new PET radiotracer can effectively visualize Nectin-4, an emerging biomarker found in triple-negative breast cancer (TNBC). According to research published in the March issue of The Journal of Nuclear Medicine, the PET tracer has the potential to play a critical role in the diagnosis, treatment, and monitoring of this aggressive disease, improving clinical outcomes for patients.
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Monoclonal antibody significantly reduces nasal polyps and need for surgery in Phase 3 clinical trial

Chronic rhinosinusitis with nasal polyps presents a substantial clinical burden, affecting nasal airflow, olfactory function, and quality of life. Epithelial barrier dysfunction and type 2 inflammatory responses drive disease progression. Treatments such as intranasal glucocorticoids and sinus surgery provide limited long-term relief and fail to address the underlying inflammatory mechanisms.
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