Compound found in rice bran can suppress intestinal contractions by inhibiting calcium influx

A research team at Toho University has revealed that ferulic acid (FA), a polyphenol abundant in rice bran, suppresses intestinal smooth muscle contractions by inhibiting voltage-dependent calcium channels. This finding may open new avenues for dietary-based strategies to manage intestinal motility disorders such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD).
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Heart disease and diabetes drive surge in deaths among Americans without college degrees

About 525,000 more deaths occurred among US adults in 2023 than would be expected had pre-2010 mortality trends continued. More than 90% of these deaths occurred among individuals without a bachelor’s degree and were largely caused by cardiovascular diseases, underscoring how educational attainment can influence individuals’ health opportunities and outcomes.
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The value of physical activity for people with RMD

Regular physical activity is increasingly promoted for people with rheumatic and musculoskeletal diseases (RMD) as well as the general population. EULAR—The European Alliance of Associations for Rheumatology—has published recommendations for physical activity in people with inflammatory arthritis and osteoarthritis. There are also points to consider on helping people participate in healthy and sustainable paid work.
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Studies show nurses play a critical role for people with rheumatic musculoskeletal diseases

EULAR—The European Alliance of Associations for Rheumatology—believes that nurses are an important part of the health care team, especially for providing evidence-based care and endorsing shared decision-making in consultation with the patient. This is also important considering the shortage of rheumatologists in Europe, which means delegation is necessary.
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First data from the EULAR RheumaFacts project

Rheumatic and musculoskeletal diseases (RMD) are the leading causes of disability worldwide, resulting in significant health care and social support costs. One of the reasons for this increasing burden seems to be the variability in the number and nature of allocated resources across Europe, as well as organizational aspects of health systems that result in disparities and health inequities across countries.
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