Novel blood test for ALS can detect early signs years before symptoms appear

By 2040, experts estimate that nearly 400,000 people worldwide will be living with amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig’s disease. This degenerative nervous system disease damages nerve cells responsible for controlling voluntary muscle movement, leading to progressive muscle weakness, loss of muscle mass and, eventually, difficulty breathing. Current ALS diagnosis relies on neurological evaluations and the presence of symptoms; at present, there is no definitive diagnostic test.
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Analysis aims to ease GI symptoms for cancer patients

Many modern cancer treatments are highly effective at reducing or eliminating tumors, but they can also cause severe gastrointestinal symptoms that impact patients’ quality of life or lead to discontinuation of treatment. A new analysis from University of Illinois Urbana-Champaign researchers reveals the nutrition therapies that are most effective at minimizing GI distress. The research is published in the journal Advances in Nutrition.
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Guideline on respiratory infections in leukemia revised

People with leukemia have a weakened immune system due to the disease itself and treatment, which leads to an increased susceptibility to infections. In a revised guideline, experts summarize the findings of the past ten years on all viruses that cause respiratory infections: How dangerous are they in detail? How are they diagnosed? Are hygiene measures necessary? What treatment and vaccination strategies are available?
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Immune cells in the brain help shape adolescent neural circuits

Making a smoothie, going for an evening walk, or having empathy for a loved one are all examples of executive functions that are controlled by the brain’s frontal cortex. This area of the brain goes through profound change throughout adolescence, and it is during this time that abnormalities in maturing circuits can set the stage for neurodevelopmental disorders, such as schizophrenia and ADHD.
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How alcohol opens the floodgates for harmful bacteria to reach the liver

Alcohol-associated liver disease (ALD) is a major cause of liver transplantation and death worldwide, and its impact is only growing. In 2022, the annual cost of ALD in the United States was $31 billion. By 2040, this number could be as high as $66 billion. ALD has limited therapeutic options, so scientists are looking for new ways to target the molecular biology of ALD to help prevent its occurrence or reduce its severity.
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