Signals from dying cells may spur liver regeneration after acetaminophen injury

Acetaminophen is the most frequently taken fever and pain medication worldwide, but overdosing can be toxic to liver cells. In the United States, about 1,600 cases of acute liver failure and 500 deaths occur each year due to acetaminophen overuse and liver failure. Although the liver has a remarkable potential to regenerate and recover from injury, scientists are seeking to better understand how this happens after acetaminophen toxicity.
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Exercise enhances stem cell transplant function in Parkinson’s disease, study finds

Parkinson’s disease (PD) is a disabling neurodegenerative disease that affects approximately 10 million people worldwide, with numbers steadily increasing. Symptoms include tremors, difficulties with movement and speech, as well as mental health issues and dementia. Although PD can be managed by medication and lifestyle adjustments, the efficacy of these interventions varies between patients and cannot stop or reverse disease progression.
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Molecular mechanism that initiates colon cancer opens new path for prevention

Colorectal cancer is the third most diagnosed type of cancer worldwide. Up to 80% of the cases are related to environmental factors and lifestyle, such as poor diet, sedentarism, obesity, smoking or excessive alcohol consumption. Most colorectal cancers arise from adenomatous polyps, a precancerous lesion that may progress to a malignant tumor unless it is detected and removed in time.
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Advanced imaging, targeted therapy help men with prostate cancer safely defer surgery and radiation therapy

In a new study led by the UCLA Health Jonsson Comprehensive Cancer Center, investigators show that using advanced MRI imaging and targeted focal therapy can help many men with low- to intermediate-risk prostate cancer safely stay on active surveillance long-term, helping avoid follow-up biopsies and delay—or even avoid—invasive treatments like surgery or radiation.
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