July 5, 2025
Hot News

A new computational framework illuminates the hidden ecology of diseased tissues

MyBlueDots01 mins
To understand what drives disease progression in tissues, scientists need more than just a snapshot of cells in isolation—they need to see where the cells are, how they interact, and how that spatial organization shifts across disease states. A computational method called MESA (Multiomics and Ecological Spatial Analysis), detailed in a study published in Nature Genetics, is helping researchers study diseased tissues in more meaningful ways.
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Antibody-based drug dismantles a metabolic barrier to anti-tumor immunity

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A Ludwig Cancer Research study has identified a specific mode of fat uptake by immune cells within tumors that serves as a metabolic checkpoint against anti-cancer immune responses. Harnessing that insight, researchers led by Ludwig Lausanne’s Ping-Chih Ho and Yi-Ru Yu—along with Sheue-Fen Tzeng and Chin-Hsien Tsai, former post-docs in the Ho lab who now lead their own labs at Taipei Medical University in Taiwan—have developed a humanized antibody to dismantle that barrier as a potential cancer immunotherapy.
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BNT162b2 vaccine not only targets COVID-19 virus, but may also help reduce and control innate inflammation

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Trinity College Dublin researchers have found that the BNT162b2 COVID-19 vaccine may offer protection beyond its intended primary target. In a study recently published in the Clinical Immunology journal, researchers found that the vaccine not only targeted the COVID-19 virus, it also unexpectedly helped to reduce and control innate inflammation of other bacterial and fungal pathogens not related to the vaccine target.
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Climate change and lack of sustainable policies may fuel rise in superbugs

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Current climate change trajectories and failing to meet sustainable development strategies could contribute to an increase in the global burden of antimicrobial resistance (AMR) by 2050, according to a study published in Nature Medicine. The authors project that AMR could increase by up to 2.4% globally by 2050, and call for urgent action to address broader socioeconomic and environmental factors beyond simply reducing antibiotic use to mitigate the global AMR burden.
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Hormone supplementation in rhesus monkeys points to potential autism treatment

MyBlueDots01 mins
For years, Florida Tech’s Catherine Talbot, an assistant professor of psychology, has worked to understand the sociality of male rhesus monkeys and how low-social monkeys can serve as a model for humans with autism. Her most recent findings show that replenishing a deficient hormone, vasopressin, helped the monkeys become more social without increasing their aggression—a discovery that could change autism treatment.
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Researchers find link between HPV and thyroid eye disease

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University of Miami Miller School of Medicine researchers have identified molecular evidence linking human papillomavirus (HPV) to thyroid eye disease (TED) through molecular mimicry involving HPV capsid proteins and autoimmune targets. Elevated antibody levels against HPV appeared in participants with TED, suggesting a possible immunological connection influencing disease development.
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