Gene therapy offers hope for rare, deadly heart disease in young men

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has developed an innovative gene-therapy strategy that could transform the treatment of arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5), a rare and highly penetrant inherited cardiac disorder with an elevated risk of sudden cardiac death. This disease is particularly devastating in young men and lacks a cure, with current treatments focusing on palliative care.
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Genetic predisposition to sedentary behavior increases the risk of cardiovascular diseases, finds study

Although sedentary behavior may be an evolutionarily selected trait, it is still important to try to be physically active, says a new study conducted at the University of Jyväskylä, Finland. Researchers have shown for the first time that genetic predisposition to sedentary behavior is associated with a higher risk of developing the most common cardiovascular diseases. A high genetic predisposition to sedentary behavior can increase the risk of cardiovascular diseases by up to 20%.
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