July 4, 2025
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How the brain uses context boundaries to guide decision-making in both spatial and abstract environments

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The DAM-Decision and Memory group at Universitat Jaume I in Castelló, led by Raphael Kaplan and composed of researchers from Spain, Italy and the United States, has recently published the results of two studies that provide new insights into human brain behavior in everyday activities such as decision-making and social interaction.
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Alteplase increases frequency of functional independence after posterior circulation stroke

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For patients with mainly mild posterior circulation ischemic stroke who do not receive thrombectomy, alteplase administered at 4.5 to 24 hours after onset results in higher frequency of functional independence at 90 days compared with standard medical care, according to a study published in the April 3 issue of the New England Journal of Medicine.
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Almost one in two Aussie teens have a chronic disease or developmental condition, says study

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New research published today shows that almost half (45.6%) of Australian teens are living with chronic diseases or developmental conditions like attention deficit hyperactivity disorder (ADHD) or autism (ASD). The study has linked the conditions to unhealthy lifestyles, diets and poor mental health, prompting calls for further research and government action.
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First step for pandemic prevention: Experts comment on WHO’s first binding national agreement

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The World Health Organization (WHO) is on the verge of adopting the world’s first binding international agreement focused on pandemic prevention. This landmark development, schedule for potential ratification at the 78th World Health Assembly in May 2025, adopts a crucial One Health approach, emphasizing the global need to curb pandemic risks at the human-animal-environment interface. Dr. Raina Plowright, Rudolf J. and Katharine L. Steffen Professor of Veterinary Medicine, along with colleagues on The Lancet Commission on Prevention of Viral Spillover, published their comment piece on the agreement in The Lancet on April 3.
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Switching from dulaglutide to tirzepatide improves HbA1c reduction in type 2 diabetes

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For patients with inadequately controlled type 2 diabetes receiving dulaglutide, switching to tirzepatide is associated with additional hemoglobin A1c (HbA1c) reduction and weight loss compared with escalating treatment with dulaglutide, according to a study published online April 4 in the Annals of Internal Medicine to coincide with the Internal Medicine Meeting, the annual meeting of the American College of Physicians, held from April 3 to 5 in New Orleans.
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