Study shows inpatient psychiatric care can help teens amid a depressive crisis

There has been a troubling rise in adolescent mental health struggles and suicide rates over the past decade, with a dramatic increase following the start of the COVID-19 pandemic. This crisis has been accompanied by an increased demand for pediatric inpatient psychiatry units (IPUs) across the United States. However, despite the growing need, which has reached the point of bed shortages, the effectiveness of IPUs on teen mental health outcomes remains understudied.
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Acute and chronic stress have markedly different impacts on neural repair in a depression-linked brain region

Researchers at Zhejiang University found that acute stress increases natural repair mechanisms in the brain, while chronic stress suppresses them. Autophagy was most affected in the lateral habenula, a brain region linked to emotional regulation. Several antidepressant drugs were tested and found to reverse this suppression, pointing to autophagy in the lateral habenula as a common therapeutic pathway in these treatments.
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